Testosterone Enanthate

Drug description

Testosterone enanthate is an anabolic steroid used in the androgen replacement therapy primarily in males with confirmed testosterone deficiency. Androgens are responsible for the alterations in male body musculature, normal growth of the sex organs, fat and hair distribution and other functions such as retention of sodium, nitrogen and potassium. The sufficient amount of androgens contributes to the creation of a balance in the body and generally exogenous androgens are produced in lower quantities, therefore its deficiency may cause a series of adverse events. Therapy with testosterone enanthate is indicated in patients with low levels of androgens and it is prescribed individually to each patient according to its medical condition. It is recommended to use testosterone enanthate only by following a medical prescription in order to avoid certain side effects it may generate.

Contraindications

·Testosterone enanthate is contraindicated in patients with a known hypersensitivity to the drug that can cause adverse reactions such as rash,

·Do not use testosterone enanthate if you have a medical evidence of prostatic carcinoma or mammary carcinoma in males.

·It is contraindicated the use of testosterone enanthate in males with evidence of hypercalcaemia.

·Also, it is contraindicated the use of this drug in patients with known liver tumours or any other form of malignant tumours.

Precautions

·As with any other drug, it is important to consult a doctor before starting the therapy with testosterone enanthate (Testoxyl Enanthate 250) because the respective drug is prescribed to patients with confirmed testosterone deficiency. Its use without confirming medical tests may lead to serious side effects.

·The main purpose of the therapy with testosterone enanthate is to keep the drug levels within the range for the age group concerned, therefore it is recommended to follow all the instructions in order to avoid the over-replacement of naturally produced testosterone.

·It is not recommended the use of testosterone enanthate for other purposes such as enhancing muscular development and increasing physical ability, especially in healthy males.

·As androgens retain the sodium, potassium, nitrogen and other elements, caution should be exercised in patients predisposed to oedema and other medical conditions. In order to avoid the occurrence or worsening of existing medical conditions, stay under the surveillance of a doctor during the whole period of therapy.

·As a general precaution, especially patients on long-term therapy with testosterone enanthate it is recommended to pass regular examinations of the prostate and periodically assess the levels of hemoglobin and hematocrit in order to detect in time the polycythemia.

·As already mentioned, testosterone enanthate is contraindicated in patients with confirmed liver tumours or prostatic carcinoma, therefore it is very important to inform the doctor about the occurrence of unusual upper abdominal pain that does not disappear in a short period of time. Such symptoms have to be reported right away in order to avoid life-threatening situations such as intra-abdominal hemorrhage caused by therapy with testosterone enathate.

·Testosterone enanthate is indicated for use in males only and it is contraindicated for use in women, due to occurrence of virilising effects. Therefore it should not be used in pregnant women as well, in order to protect the fetus from undesirable adverse reactions.

·Caution should be exercised in males with liver impairment. There are no supportive medical studies in this sense, therefore it should be used either in lower doses than normal or replaced with other androgen replacement therapy more safe for such patients.

·Also, it should not be used in patients with impaired renal function.

Interaction with other drugs

Like any other drug, testosterone should be used cautiously when on therapy with other medicines. It is important to inform your doctor about all the medicines you are currently taking, before starting to use testosterone enanthate in order to avoid any side effects. There are clinical studies that state that testosterone should not be used while taking phenobarbital, as it increases the breakdown of steroid hormones in the liver. Also, it is not recommended the concomitant use of the testosterone enanthate with coumarin derivatives, and if this is the case then a doctor should closely monitor the patient.

Possible adverse effects with testosterone enanthate

Like any other anabolic steroid, testosterone enanthate may cause adverse reactions. The most reported adverse effects from the use of this drug are the following:

·Injection site pain, erythema, inflammation and swelling are considered the usual skin reactions, however these should not be tolerated. Patient should consult a doctor in order to avoid the occurrence of systematic skin injury.

·Dyspnea or cough right away after the injection of the drug;

·Chest pain.

Other adverse reactions that may occur after the use of testosterone enanthate are the following:

·Dizziness;

·Malaise;

·Paraesthesia;

·Syncope;

·Hyperhidrosis, especially in males on high-dosed or long-term administration of the drug;

·Persistent or frequent erections, in this case it is recommended either the immediate discontinuation of the drug or reducing the administered dose in order to avoid injury to the penis.

·Skin care side effects such as acne, rash, pruritus.

·Gynaecomastia;

·Alopecia;

·Jaundice and other side effects.

In order to avoid any serious side effects, refer to the precautions before starting to use it. Consult a doctor on a regular basis and make all necessary laboratory tests in order to prevent the occurrence or worsening of existing medical conditions.

Indications of use and dosage

Testosterone enanthate is an anabolic steroid that comes in form of injectable oily solution. It is necessary to inject the drug intramuscularly. In order to determine the dosage each patient should consult a doctor because all the doses are set individually considering the medical condition of the patient. Generally, the therapy is divided into phases: initial phase and maintenance phase. Usually, in the initial phase of treatment it is indicated 1 prefilled syringe every 2-3 weeks. One prefilled syringe contains 250mg of testosterone enanthate. In the maintenance phase it is indicated 1 prefilled syringe every 3-4 weeks. Before starting the therapy it is important to measure the testosterone levels and on a regular basis during the treatment. If overdose is detected, consult a doctor right away and take all the measures in order to eliminate any risks or side effects. Testosterone enanthate is not toxic; therefore overdose cases are very rare.

Storage conditions

It is recommended to store testosterone enanthate in a clean and dry place at the temperature below 25 degrees Celsius and out of the reach of children.